14 former FCS players were selected in the 2019 NFL Draft.
Here’s a look at all of the picks from the subdivision:
| Rd. | No. | Team | Player | Pos. | College |
| 1 | 23 | Houston | Tytus Howard | OT | Alabama State |
| 2 | 34 | Indianapolis | Rock Ya-Sin | CB | Presbyterian/Temple |
| 2 | 60 | LA Chargers | Nasir Adderley | FS | Delaware |
| 3 | 84 | Kansas City | Khalen Saunders | DT | Western Illinois |
| 3 | 98 | Jacksonville | Quincy Williams | SS | Murray State |
| 5 | 166 | LA Chargers | Easton Stick | QB | North Dakota State |
| 6 | 189 | Cleveland | Drew Forbes | OG | Southeast Missouri State |
| 6 | 193 | Minnesota | Oli Udoh | OT | Elon |
| 7 | 223 | Cincinnati | Jordan Brown | CB | South Dakota State |
| 7 | 225 | Buffalo | Darryl Johnson | DE | North Carolina A&T |
| 7 | 227 | Washington | Jimmy Moreland | CB | James Madison |
| 7 | 230 | Oakland | Quinton Bell | OLB | Prairie View A&M |
| 7 | 244 | New Orleans | Kaden Elliss | OLB | Idaho |
| 7 | 248 | Arizona | Joshua Miles | OG | Morgan State |
